Fred Jones, Jr., Daphne Blake, Velma Dinkley, Norville "Shaggy" Rogers, and Scooby-Doo are a team of teenage mystery solvers who live in the small town of Crystal Cove, the self-proclaimed "Most Hauntedest Place on Earth".The allegedly "cursed" town's long history of strange disappearances and ghost and monster sightings form the basis for its thriving tourist industry; as such, the adults of the town (chief among them being Fred's father Mayor Fred Jones Sr.and Sheriff Bronson Stone) are not happy that the kids are debunking all the supernatural goings-on that bring in so much revenue as the overwrought schemes of charlatans and criminals.
The series pays homage to the horror genre, drawing on many works from film, television and literature in both parodic and serious ways, from horror movie classics like A Nightmare on Elm Street, modern films such as Saw, television series Twin Peaks, and the works of H. Lovecraft, alongside the classic monster horror movies shown in previous series.
In particular, in the second season, the central story arc evolves to heavily feature the use of Babylonian mythology, exploring the Anunnaki, the Babylonian and modern pseudo-scientific concepts of Nibiru, and the writings of Zecharia Sitchin.
Other Hanna-Barbera characters occasionally guest-star, including Captain Caveman, Jabberjaw, Speed Buggy, The Funky Phantom, Blue Falcon and Dynomutt, and more.
As was the case with the previous three installments in the franchise, Mystery Incorporated redesigns the main characters, this time into a retro look that returns them to their original 1969 outfits, with some small changes (such as Velma now wearing bows in her hair).
The series is also the animated debut of Matthew Lillard as the voice of Shaggy, after he portrayed the character in two live-action films, Scooby-Doo (2002) and Scooby-Doo 2: Monsters Unleashed (2004).
Casey Kasem, the original voice of Shaggy, voiced Shaggy's father in five episodes; this would be his last voice-acting role before his death.
Linda Cardellini, who played Velma in the live-action movies, voiced Hot Dog Water, a recurring character in the series.
The show also brought back characters seen in previous Scooby-Doo series such as the eco-goth rock band The Hex Girls and Vincent Van Ghoul from The 13 Ghosts of Scooby-Doo, though his character is this time portrayed as a direct homage to Vincent Price, being a famous horror movie actor rather than an actual warlock.
Mystery Incorporated (also known as Mystery Incorporated or Scooby-Doo!
Mystery, Inc.) is the eleventh incarnation of Hanna-Barbera's Scooby-Doo animated series, and the first incarnation not to be first-run on Saturday mornings. Animation and Cartoon Network and premiered in the United States on Cartoon Network on April 5, 2010, with the next twelve episodes continuing, and the first episode re-airing, on July 12, 2010.
The series concluded on April 5, 2013 with two seasons and fifty-two episodes, with a total of twenty-six episodes per season.